Brock Lesnar and Cain Velasquez first fought in the Ultimate Fighting Championship (UFC) on October 23, 2010 at UFC 121. Velasquez, a former collegiate wrestler, defeated Lesnar, the reigning heavyweight champion, in the first round by TKO (technical knockout).
Their fight was highly anticipated as Lesnar was considered one of the most dominant heavyweight fighters in the UFC at the time, while Velasquez was seen as a rising star in the division. Velasquez's victory marked the end of Lesnar's reign as champion and solidified Velasquez as the new heavyweight champion.
The two fighters were scheduled to have a rematch at UFC 196 in 2016, but Velasquez had to pull out due to injury. The rematch did not end up happening in the UFC, but Lesnar and Velasquez did face off again in a professional wrestling match in WWE in 2019.
Overall, Lesnar vs. Velasquez is a significant fight in the history of heavyweight MMA and is remembered for Velasquez's decisive victory over the then-dominant Lesnar.
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